William F. DeGrado
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SAS/ Biochemistry & Biophysics; Chemistry

De novo design of proteins, peptide design, and small molecule mimics of peptides and proteins; structure, stability, and function of membrane proteins; design of biomimetic polymers; bioinorganic chemistry; computational approaches to small molecule and protein design.

Fry HC, Lehmann A, Saven JG, DeGrado WF, Therien MJ. Computational Design and Elaboration of a de Novo Heterotetrameric alpha-Helical Protein That Selectively Binds an Emissive Abiological (Porphinato)zinc Chromophore. J Am Chem Soc. 2010